Acute Appendicitis: Diagnosis and Management
Written by Dr. Muhammad Salar Raza · Manually reviewed by Dr. Muhammad Salar Raza · Content updated
Clinical Pathway
Suspect appendicitis when periumbilical pain migrates to the right iliac fossa with anorexia, low-grade fever, and localized guarding. Examine for McBurney point tenderness, rebound, and Rovsing sign, and support the diagnosis with neutrophilia and elevated CRP. Ultrasound is the first imaging choice in children and pregnancy, with CT for equivocal adults. Definitive treatment is appendectomy, usually laparoscopic, after intravenous fluids, analgesia, and preoperative antibiotics. Perforated appendicitis with generalized peritonitis needs urgent surgery and broader antibiotics, while a stable contained appendiceal mass may be managed with antibiotics and interval appendectomy. Do not delay surgery for prolonged observation once the diagnosis is clear.
Clinical Reasoning
The migration of pain from the umbilicus to the right iliac fossa reflects the shift from visceral to parietal peritoneal irritation and is the highest-yield historical clue. Rebound tenderness and guarding indicate peritonitis and mandate urgent surgical review rather than more tests. Atypical presentations are the traps: retrocecal appendicitis causes flank pain with a positive psoas sign, and pelvic appendicitis irritates the bladder or rectum with minimal abdominal signs. In pregnancy the appendix migrates upward, displacing tenderness. A completely normal white cell count does not exclude early appendicitis, and analgesia does not mask a surgical abdomen and should not be withheld.
Sample MCQ
A 22-year-old man has 18 hours of pain that began around the umbilicus and shifted to the right iliac fossa. He has fever 38.1 degrees Celsius, anorexia, localized rebound tenderness at McBurney point, and a white cell count of 15,000. What is the most appropriate management?
- AAppendectomy with perioperative antibiotics
- BDischarge with oral analgesia and review in 1 week
- COutpatient colonoscopy
- DHigh-fibre diet and laxatives
Correct Answer: Appendectomy with perioperative antibiotics
Migratory pain, localized rebound tenderness, fever, and neutrophilia establish acute appendicitis with peritoneal irritation, and prompt appendectomy with perioperative antibiotics is the standard treatment; delay risks perforation. Discharge with analgesia is unsafe because progression to perforation and peritonitis can occur within 24-48 hours. Colonoscopy has no role in suspected appendicitis and could be harmful. Dietary measures and laxatives address constipation, and laxatives in particular are dangerous in a possible surgical abdomen because they can precipitate perforation.
Guidelines and further reading
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